Small regulatory RNAs in Archaea
نویسندگان
چکیده
منابع مشابه
Small regulatory RNAs in Archaea
Small regulatory RNAs (sRNAs) are universally distributed in all three domains of life, Archaea, Bacteria, and Eukaryotes. In bacteria, sRNAs typically function by binding near the translation start site of their target mRNAs and thereby inhibit or activate translation. In eukaryotes, miRNAs and siRNAs typically bind to the 3'-untranslated region (3'-UTR) of their target mRNAs and influence tra...
متن کاملHomologs of small nucleolar RNAs in Archaea.
In eukaryotes, dozens of posttranscriptional modifications are directed to specific nucleotides in ribosomal RNAs (rRNAs) by small nucleolar RNAs (snoRNAs). We identified homologs of snoRNA genes in both branches of the Archaea. Eighteen small sno-like RNAs (sRNAs) were cloned from the archaeon Sulfolobus acidocaldarius by coimmunoprecipitation with archaeal fibrillarin and NOP56, the homologs ...
متن کاملRegulatory RNAs in archaea: first target identification in Methanoarchaea.
sRNAs (small non-coding RNAs) representing important players in many cellular and regulatory processes have been identified in all three domains of life. In Eukarya and Bacteria, functions have been assigned for many sRNAs, whereas the sRNA populations in Archaea are considerably less well characterized. Recent analyses on a genome-wide scale particularly using high-throughput sequencing techni...
متن کاملSmall regulatory RNAs in mammals.
Mammalian cells harbor numerous small non-protein-coding RNAs, including small nucleolar RNAs (snoRNAs), microRNAs (miRNAs), short interfering RNAs (siRNAs) and small double-stranded RNAs, which regulate gene expression at many levels including chromatin architecture, RNA editing, RNA stability, translation, and quite possibly transcription and splicing. These RNAs are processed by multistep pa...
متن کاملComparative Detection of Processed Small RNAs in Archaea
Enzymatic splicing in Archaeal tRNAs is guided by bulgehelix-bulge structural elements, while much less seems to be known about splicing in other small RNAs (sRNAs). We conduct a genome-wide analysis of several archaeal genomes to identify putative BHB elements and compare our findings with available RNA-seq data. We also provide an analysis of the viability of using pattern-based and stochasti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: RNA Biology
سال: 2014
ISSN: 1547-6286,1555-8584
DOI: 10.4161/rna.28452